Cell phones work by sending signals to (and receiving them from) nearby cell towers (base stations) using RF waves. This is a form of electromagnetic energy that falls between FM radio waves and microwaves. Like FM radio waves, microwaves, visible light, and heat, RF waves are a form of non-ionizing radiation. They don’t have enough energy to cause cancer by directly damaging the DNA inside cells. RF waves are different from stronger (ionizing) types of radiation such as x-rays, gamma rays, and ultraviolet (UV) light, which can break the chemical bonds in DNA.
A series of studies testing different scenarios (called simulations by the study authors) were carried out using incidence data from the Nordic countries to determine the likelihood of detecting various levels of risk as reported in studies of cell phone use and brain tumors between 1979 and 2008. The results were compatible with no increased risks from cell phones, as reported by most epidemiologic studies. The findings did suggest that the increase reported among the subset of heaviest regular users in the Interphone study could not be ruled out but was unlikely. The highly increased risks reported in the Swedish pooled analysis were strongly inconsistent with the observed glioma rates in the Nordic countries (24).
That’s why randomized controlled trials (RCTs) often yield fairly clear answers about the effectiveness of treatments compared to other study designs. (Fun fact: Scottish doctor James Lind, a clinical trial pioneer, figured out that citrus fruits seemed to have an effect on scurvy using one of the earliest RCTs.) RCTs can also be used to study whether something, like cellphone radiation, can cause disease.
While driving, it is best to talk as little as possible on the mobile phone, and in any event, follow regulation 28(b) of the traffic regulations. This regulation stipulates that: “While a vehicle is in motion, the driver of the vehicle will not hold a stationary or mobile phone, and will not use then in the vehicle unless when using a speakerphone; and will not send or read a text message (SMS)”.
A 2010 review stated that "The balance of experimental evidence does not support an effect of 'non-thermal' radiofrequency fields" on the permeability of the blood-brain barrier, but noted that research on low frequency effects and effects in humans was sparse. A 2012 study of low-frequency radiation on humans found "no evidence for acute effects of short-term mobile phone radiation on cerebral blood flow".
Over time, the number of cell phone calls per day, the length of each call, and the amount of time people use cell phones have increased. Because of changes in cell phone technology and increases in the number of base stations for transmitting wireless signals, the exposure from cell phone use—power output—has changed, mostly lowered, in many regions of the United States (1).