As to increases in brain tumors tied to cell phone use, it’s too early to tell due to a lack of hard data, says Dr. Carlo. “We’re never going to see that in time to have it matter. Here in the US, we’re six years behind in getting the brain tumor database completed, and currently the best data are from 1999. By the time you see any data showing an increase, the ticking time bomb is set.”
Unfortunately, however, we’ll probably never have an RCT on cellphones and cancer in humans. It’d be too difficult and too expensive to randomly assign particular levels of cellphone use to thousands of people and have them stick with those plans for enough time (we’re talking at least five years) to figure out whether certain types of phones or phone use patterns cause cancer to develop. That’s not to mention the fact it’d be nearly impossible to find a group of people willing to not use cellphones and then make sure they actually stick to their promise.
Taken together, the findings “confirm that RF radiation exposure has biological effects” in rats, some of them “relevant to carcinogenesis,” says Jon Samet, a professor of preventive medicine and dean of the Colorado School of Public Health, who did not participate in either study. Samet, however, cautioned the jury is still out as to whether wireless technology is similarly risky to people. Indeed, heart schwannomas are exceedingly rare in humans; only a handful of cases have ever been documented in the medical literature.
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Another animal study, in which rats were exposed 7 days per week for 19 hours per day to radiofrequency radiation at 0.001, 0.03, and 0.1 watts per kilogram of body weight was reported by investigators at the Italian Ramazzini Institute (35). Among the rats with the highest exposure levels, the researchers noted an increase in heart schwannomas in male rats and non-malignant Schwann cell growth in the heart in male and female rats. However, key details necessary for interpretation of the results were missing: exposure methods, other standard operating procedures, and nutritional/feeding aspects. The gaps in the report from the study raise questions that have not been resolved.
The city council of Berkeley, Calif., has also acted. In May 2015, it approved a “Right to Know” law that requires electronics retailers to notify consumers about the proper handling of cell phones. CTIA-The Wireless Association, a trade group, is now trying to block that law from going into effect, as it successfully did after San Francisco passed its own Right to Know law five years ago.
Overall, the reviews of case-control studies seem to suggest there is perhaps no risk of cancer with cellphone use — unless you look at some subgroups (like people in blinded studies or people with long-term exposures). But these reviews are based on case-control studies — which are like the National Enquirer of the science world: cheap and often misleading.
A large, long-term study has been comparing all of the people in Denmark who had a cell phone subscription between 1982 and 1995 (about 400,000 people) to those without a subscription to look for a possible increase in brain tumors. The most recent update of the study followed people through 2007. Cell phone use, even for more than 13 years, was not linked with an increased risk of brain tumors, salivary gland tumors, or cancer overall, nor was there a link with any brain tumor subtypes or with tumors in any location within the brain.