I really want to caution you to be careful of any "expert" or EMF blogger recommending anti-radiation filtering cases, stickers that attach to the phone or necklaces to "ward off" EMF.  I get it, when I first realized 25 years ago that I was sensitive to electromagnetic energy and then later, when I understood that without a doubt, man made electromagnetic radiation has a biological effect on my body, I wanted an easy fix.  I tried the shielding materials and cases and I just did not feel any better.  Then I bought meters to see if the energy changed and I actually noticed what the California Department of Health now says and it's what the FTC and FCC post warnings about:  "Some shielding materials can make exposures worse". So please, be careful and read on for what you can do to avoid electromagnetic radiation exposure.
If you want to use your phone for talking, then the idea is that you keep it flipped over the front of the screen – that way you’re blocking radiation on both the front and back. The speaker still works with the cover on, because there’s a small hole for that. The inevitable drawback of this is that you have to flip the cover open in order to access your keypad.
This is the second Cell Shield protector I have purchased. I have had one for my cell phone for almost a year now and it has been wonderful! When my husband upgraded to a new phone, I knew I needed to purchase one for him. The application of the button is very simple and it stays on well. Due to the fact that it is a 'raised' button (a few millimeters thick), some may find it difficult to know where to apply it. I have an i4 phone with an Otterbox case. There is a round cut-out hole in the case that lines up with the 'apple' symbol on the back of the phone. I was able to place the button in that cut-out and it lines up flush with the cover. I highly recommend this Protector to anyone looking to significantly and effectively block EMF's.
A 2010 review stated that "The balance of experimental evidence does not support an effect of 'non-thermal' radiofrequency fields" on the permeability of the blood-brain barrier, but noted that research on low frequency effects and effects in humans was sparse.[4] A 2012 study of low-frequency radiation on humans found "no evidence for acute effects of short-term mobile phone radiation on cerebral blood flow".[5][6]
Cell phones emit low levels of radio frequency energy (i.e., radio frequency radiation) in the microwave range while being used. It is well known that high levels of RF can produce biological damage through heating effects (this is how your microwave oven is able to cook food). However, it is not known to what extent or through what mechanism, lower levels of RF might cause adverse health effects as well. Several research studies have shown that the radio frequency radiation from wireless phone antennae “appears to cause genetic damage in human blood,” while another case study uncovered a “statistically significant increase” in neuro-epithelial brain tumors among cell phone users. Other research has shown little or no adverse effects. ABC’s 20/20 News (May 26, 2000) took the five most popular phones sold in the US and tested them at a highly respected German laboratory. Four out of the five phones tested were above the SAR limit. One thing is for certain, similar to the case of cigarette smoking, it will take several tests and many years before the effects of radio frequency radiation on the human body are known.
It’s true that cellphones do emit radiation. And radiation is a scary word for a lot of people, thanks in part to the horrific aftermath of nuclear accidents and photographs of victims of the nuclear bombs the US dropped on Japan in World War II. People hear radiation and they associate it with nuclear radiation and the bomb, says Geoffrey Kabat, a cancer epidemiologist at the Albert Einstein College of Medicine and author of the book Getting Risk Right. “There are all these associations and those are deeply ingrained in people. But it doesn’t apply here.”
I'm glad I spent the money to get this protection. Again, I consider this an "insurance policy" and hope cell phone radiation is over hyped. However, mounting evidence seems to indicate otherwise, so I feel more comfortable knowing I'm taking proactive steps to protect against a possible health problem I and my family might face in the future from long and close exposure to cell phones close to the body and head.
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SafeSleeve Anti Radiation Case: Safe Sleeve website says they integrate FCC accredited independent lab tested "shielding technology" in their products. There are many links to "SafeSleeve, Is it a Scam?" and "Does SafeSleeve work?" online, but if you follow those links you'll find they go to the actual SafeSleeve site where the question of SafeSleeve protection is addressed.  You'll see in this demonstration that the radiation level was higher with the SafeSleeve Case on.
When you talk, your voice is transmitted from the antenna as radio frequency radiation (RFR) between 800 MHz and 2,200 MHz. A range equal to the middle of microwave frequency and 20% to 80% of the radiation emitted is deposited in the user's head. The microwave radiation is absorbed and penetrates the area around the head, some reaching an inch, to an inch and a half into the brain. Exposure to this microwave RFR has shown to have serious health consequences. Laboratory studies have shown that radiation from cell phones expose the user to a wide range of health problems including: 

*SAR values are from tests conducted by Pong Research Corp on March 29, 2012 and submitted to the FCC on May 31, 2012. Because the SAR values were submitted to the FCC in graph form, EWG estimated numerical SAR values based on the chart available in WT Docket 11-186 (http://apps.fcc.gov/ecfs/document/view?id=7021921006). Pong’s filing to the FCC did not indicate whether SAR measurements were done at the head or in a body-worn configuration. In a personal communication, Pong informed EWG that the SAR measurements were done in a body-worn configuration, with the same distance from the test mannequin used by the phone manufacturer. Tests in the body-worn configuration were done at a 10 millimeter separation distance.
Scientists have reported adverse health effects of using mobile phones including changes in brain activity, reaction times, and sleep patterns. More studies are underway to try to confirm these findings. When mobile phones are used very close to some medical devices (including pacemakers, implantable defibrillators, and certain hearing aids) there is the possibility of causing interference with their operation. There is also the potential of interference between mobile phones signals and aircraft electronics. Some countries have licensed mobile phone use on aircraft during flight using systems that control the phone output power.

A study by the Corporate EME Research Laboratory and Motorola Florida Research Laboratories tested 9 different cell phone radiation shields, 5 of which claimed to block 99% of cell phone radiation. The other 4 shields tested claimed to emit a reverse radiation that would cancel out the harmful radiation from cell phones. The study found that all of the radiation shields had no effect on the amount of radiofrequency radiation a cell phone user is exposed to from their phone.[2]
What are the health effects of mobile phones and wireless radiation? While Australia has led the world in safety standards, including compulsory seat-belt legislation, plain packaging on cigarettes, and product and food disclosure legislation, it falls behind in addressing the significant issues associated with mobile phone use. In this Dean’s Lecture, epidemiologist and electromagnetic radiation expert, Dr Devra Davis, will outline the evolution of the mobile phone and smartphone, and provide a background to the current 19 year old radiation safety standards (SAR), policy developments and international legislation. New global studies on the health consequences of mobile/wireless radiation will be presented, including children’s exposure and risks.
None of the three cases contain metallic parts, which are known to affect SAR, but all increased the user’s radiation exposure. The effect on radiation exposure would likely vary with each of the hundreds of cases on the market, and each would have to be tested individually to come up with an exact measure. The results in Table 1, however, are believed to reflect the range of radiation increases.
Yes, the information transferred between the base unit (the phone’s stationary unit) and the wireless phone’s mobile unit is transferred as radiowave radiation. Therefore, the “precautionary principle” should also be adopted regarding wireless phones. In addition to the guidelines regarding mobile phones, the Ministry of Health recommends regarding wireless phones:
What the study showed: Most published analyses from this study have shown no statistically significant increases in brain or central nervous system cancers related to higher amounts of cell phone use. One analysis showed a statistically significant, although modest, increase in the risk of glioma among the small proportion of study participants who spent the most total time on cell phone calls. However, the researchers considered this finding inconclusive because they felt that the amount of use reported by some respondents was unlikely and because the participants who reported lower levels of use appeared to have a slightly reduced risk of brain cancer compared with people who did not use cell phones regularly (4–6).